Symbiosolv Clear Plus

Manufacturing procedure for aqueous solutions or surfactant-based products (laboratory scale)

1. Pre-mix symbio®solv clear plus MB with perfume and other lipophilic substances to be solubilized at room temperature.

2. Add water, the aqueous phase or the surfactant base, to the pre-mix under stirring.

3. Adjust pH to 4.5 – 6.5 if necessary.

4. If required, add ethanol at the end of the formulation process, in small portions.

Note: In surfactant-based products: symbio®solv clear plus MB may reduce the viscosity. Adjust viscosity at the end of the formulation process.

Finding the right dosage of symbio®solv clear plus MB: dosage depends on specific lipophilic component.

For the beginning, start with a ratio of 1 : 3 (one part oil, three parts solubilizer). If the solution stays milky, increase amount of solubilizer.
In this case, you would restart the formulation.

• Working with ethanol (max. 10%): if turbid after ethanol addition, it might help to add some more solubilizer afterwards.

▪ In case of pH drift, use buffer system (e. g. TriSodium Citrate).

Usage level for a  Transparent aqueous solution Dosage (ratio) 1 : 3 – 1 : 5 (oil : solubilizer) max. 4 – 5%

Surfactant-based products 0.5 – 1.5%