Glucono delta-Lactone (Poly-Hydroxy Acid)

Price range: $4.50 through $48.00 USD

INCI: Gluconolactone

Use: 0.5 -5.0%

Solubility: Hydrophilic

DOCUMENTS (view/download): SDS | COA: #562 | #105

Gluconolactone is a naturally derived, water-soluble Polyhydroxy Acid (PHA) that provides gentle chemical exfoliation perfectly suited for sensitive skin. Unlike Alpha Hydroxy Acids (AHAs), Gluconolactone has a larger molecular structure, resulting in a slower penetration rate that minimizes irritation while delivering effective exfoliation. This unique property makes it safe for daily use, offering a balanced approach to smoothing, brightening, and renewing the complexion.

In addition to exfoliation, Gluconolactone is a powerful humectant, attracting and binding water to the skin for long-lasting hydration. It also functions as an antioxidant, chelating agent, and anti-inflammatory, supporting overall skin health and barrier function.

  • Gentle exfoliation – removes dead skin cells without irritation

  • Hydrating – enhances skin moisture retention while exfoliating

  • Antioxidant protection – helps fight free radicals

  • Chelating agent – binds heavy metals, offering EDTA replacement potential

  • Anti-inflammatory – soothes and calms sensitive skin

  • Improves skin tone & texture – promotes a brighter, smoother complexion

  • Preservative enhancer – supports formulation stability


 

  • Form: White, odorless crystalline powder

  • Solubility: Water-soluble

  • Origin: Corn starch (fermentation-derived)

  • Use Level: 0.5 – 15% (typical 0.5 – 5% in skincare; higher for peels)

  • pH Range: 3.8 – 8 (peeling effect at lower pH ~3–4)

  • Certifications: COSMOS, NATRUE approved; Vegan suitable; Kosher & Halal certified; readily biodegradable
  • Facial & body lotions

  • Creams & serums

  • Toners & essences

  • Cleansers & scrubs

  • Shampoos & conditioners

  • Exfoliating gels & peels

  • Incorporate into the water phase of formulations.

  • Stable across a wide pH range; adjust to pH 3–4 for maximum exfoliation effect.

  • Compatible with sensitive skin formulations where AHAs may be too aggressive.

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