Andrographis Extract in Butylene Glycol is derived from the leaves of Andrographis paniculata, contains andrographolide — the key bioactive compound known as the “King of Bitters.” Delivered in a butylene glycol carrier for stability and formulation ease, this extract provides multi-functional skin benefits, including potent antioxidant protection, anti-inflammatory support, skin brightening, and under-eye care.
Andrographolide works by inhibiting Platelet Activating Factor (PAF), reducing allergenic inflammation and sting responses. It boosts antioxidant defenses by increasing superoxide dismutase (SOD) and catalase, protecting glutathione levels, and reducing ROS production, lipid peroxidation, and nitric oxide levels In addition, its vasoconstrictive action and inhibition of Endothelin-1 (ET-1) release make it highly effective for reducing dark circles and evening skin tone
Product Benefits
Antioxidant Defense – Protects against oxidative stress by reducing isoprostane levels and boosting natural antioxidant enzymes.
Soothing & Anti-Irritant – Reduces allergenic inflammation, redness, and sting sensations by blocking PAF activity.
Skin Brightening – Inhibits ET-1 release from keratinocytes, lightening skin tone more effectively than kojic acid; synergistic with licorice extract.
Eye Care – Vasoconstrictor and anti-angiogenic properties help diminish dark circles and puffiness.
Anti-Aging & Protective – Reduces oxidative damage, prevents inflammation-driven aging, and supports healthy skin barrier function.
Applications
Andrographis Extract in Butylene Glycol is highly versatile and can be used in a variety of cosmetic applications:
Serums & Essences – For calming and protective benefits in lightweight, water-based formats.
Moisturizers & Creams – To provide soothing care and strengthen the skin barrier.
After-sun & Sensitive Skin Care – Reduces redness and discomfort caused by environmental stress.
Anti-Aging Formulations – Complements other actives by reducing oxidative damage and inflammation.
Personal Care Products – Can be added to toners, masks, and cleansers for added skin benefits.
Formulation Advice
Add during the cool-down phase (<40°C) to preserve bioactivity.
Works well in serums, eye creams, brightening treatments, sensitive-skin moisturizers, and anti-aging formulations.
Pairs synergistically with licorice extract for enhanced skin-lightening and even-tone benefits.
Recommended in eye care products for reducing under-eye darkness, puffiness, and irritation.
Specifications
Form: Liquid
Use Level: 1.0 – 10.0%
Solubility: Water-soluble
pH Range: 4.0 – 7.0
Enviornmental Considerations
Andrographis paniculata has a long heritage in Ayurvedic and traditional Chinese medicine for its “cooling” and protective qualities. By isolating high-purity andrographolide and delivering it in a stable butylene glycol carrier, this extract enables formulators to harness powerful traditional botanicals in modern, clinically relevant skincare. Its multi-benefit activity also allows formulators to replace multiple actives with one ingredient, supporting both formulation simplicity and sustainable product design.
INCI:Andrographis Paniculata Extract, Butylene glycol, Aqua
Use: 1 – 10%
Solubility: Soluble
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