Allantoin is a crystallized oxidation product of uric acid found naturally in many plants. It enhances the efficacy and appeal of dermatological and cosmetic formulations by acting as a skin protectant and providing necessary hydration. The addition of Allantoin to cosmetic formulations results in softer, suppler skin. In addition to moisturizing, Allantoin also helps to gently exfoliate the skin by softening the top layer of skin. Because of its soothing properties as a keratolytic agent, it can be a great ingredient in formulations developed to reduce dullness or for sensitive, acne-prone skin. Since Allantoin is both a skin protectant and moisturizer, it helps protect against trans-epidermal water loss. Preventing moisture loss is important for calming irritated skin and improving skin texture for all skin types.

Allantoin has been used in a wide variety of personal care products and cosmetics for decades due to its gentleness and effectiveness including:

Skincare use for

Creams, lotions and cleansers for the face, hands and body
Lip balms
Shave and Aftershave products
Serums, toners and masks
Sunscreens
Bath and shower products
Makeup and cosmetics
Haircare
Infant products

Most emollients, such as allantoin, are generally considered safe for human use on a daily basis, as well as safe for the environment. The US FDA has classified allantoin as an OTC Category I active ingredient (safe) for use at 0.5% to 2.0%. In addition, this means that allantoin is effective as a skin protectant even at low concentrations for cosmetic use. The FDA has approved the following statements for nonprescription drug products containing 0.5% – 2.0%:
For the temporary protection of minor cuts, scraps, burns and sunburn
Helps prevent and temporarily protect chafed, chapped, cracked or wind-burned skin and lips.
Relieves dryness, and softens cold sores and fever blisters
Helps treat and prevent diaper rash. And protects chafed skin/minor skin irritation due to/associated with diaper rash and helps protect from/seal out wetness.